Temporary campus guidelines for any gathering other than academic classes, professional education programs (GTPE), or department meetings are available at specialevents.gatech.edu/fall-2020-events.


Thursday, February 20 2020
12:00pm - 1:00pm
Krone Engineered Biosystems Building, Room 5029 - Atlanta, GA
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Biopolymer Characterization Core Seminar

This presentation will cover the principles of operation and theory of the methods; experimental design and sample requirements; examples of applications in the study of binding interactions of biological molecules and their thermal stability.  Light refreshments served. RSVP by 02/13/2020 to ernie.fox@malvern.com 

Test for binding affinity with ITC or thermal stability with DSC 

  • No label needed 
  • Done directly in solution 
  • Information you get from ITC: KD , stoichiometry...
  • Information you get from DSC: Tm ...

Some of the sample types that can be tested on the MicroCal PEAQ ITC and DSC: 

ITC 

  • Protein, protein interactions 
  • Protein, small molecule interaction 
  • Protein, DNA and RNA interaction 
  • Nanoparticles, protein interaction 
  • Nanoparticles, DNA/ RNA interaction 
  • And more… 

DSC 

  • Protein 
  • Nucleic acids 
  • Liposomes 
  • Virus or VLP 
  • And more…